The flowprobe™ is a real-time in situ microextraction technology for quantitative and qualitative analysis by mass spectrometry. The flowprobe system is based on the Liquid-Microjunction Surface Sampling Probe (LMJ-SSP) technology developed under Dr. Gary Van Berkel at Oak Ridge National Laboratory. The flowprobe’s continuous solvent flow enables it to obtain analyte with the highest extraction efficiency of any commercially available technology for ambient mass spectrometry. Amenable to spot sampling and imaging a range of surfaces--from cells and tissues to analytic/polymeric substrates—it can accelerate drug distribution studies, cancer and microorganism profiling, and biochemical analyses.
The flowprobe features probe hardware that makes maintenance simple and reproducible. With the flowprobe, both spot sampling and line scanning are possible providing flexibility for your workflows.
An intuitive software GUI enables:
- Precise movement of the probe and surface platform
- Optical image overlay on the graphical surface display
- Sample height measurement for tight control of the liquid junction
- Spot Sampling, Line Scanning, and Rastering for MS Imaging
- Saving methods to repeat later
The flowprobe will be available as an add-on kit to existing OS-3201 DESI 2D systems and as a complete system for select Thermo Scientific mass spectrometers. AB Sciex compatible units are in development.
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Applications of the Flowprobe are highly diverse and include sample types of the following:
- Analytical surface blots
- Bacterial colonies
- Films and packaging materials
- Fungal growths
- Protein arrays
- HPTLC/TLC plates
- Thin tissue sections
If your application is not listed, we can explore the feasibility of your application using Prosolia's Direct Laboratory Services.
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|Model No.||Instrument Model|
|FP-3200||Exactive Series, LCQ Fleet, LTQ Series, Orbitrap Series|