News Release

Inproteo/Prosolia Announce Technology License

Indianapolis, May 16, 2005—Inproteo has announced an agreement to license certain rights to the Desorption Electrospray Ionization (DESI) technology to Prosolia. The DESI technology is a proprietary ionization technique from the laboratory of Dr. R. Graham Cooks, Aston Laboratories of Mass Spectrometry at Purdue University, West Lafayette, Indiana. This technology allows protein complexes to be ionized with retention of their conformation and function. The revolutionary technology allows mass spectra to be obtained almost anywhere at ambient temperatures, from inert surfaces or directly from living tissues with no sample preparation.

Dr. John Campbell, president and CEO of Prosolia, stated, “We are delighted to have this additional technology added to our portfolio of product offerings. DESI has already generated considerable interest within the mass spectrometry community and upon full commercialization will revolutionize the field of mass spectrometry. This technology will change what mass spectrometers can do, where mass spectrometers are used and who uses them. We now have the rights to manufacture and market stand-alone DESI ionization sources to the research community and to incorporate this technology into our other products.”

Dr. John Hurrell, President of Inproteo, commented, “Ambient environmental Desorption Electrospray Ionization Mass Spectrometry is a disruptive technology that will find wide ranging uses across most areas of analytical chemistry and chemical monitoring. Inproteo wants to introduce this technology to the research community as quickly as possible and has licensed Prosolia so that stand-alone ion sources for the standard mass spectrometer will be available shortly. Prosolia has moved quickly in order to develop the ionization sources in a user friendly configuration so that researchers will be able to easily install the source and immediately begin to generate meaningful data.”

About Prosolia:
Prosolia was established in 2003 to commercialize certain innovations in mass spectrometry arising in the laboratory of Dr. R. Graham Cooks at Purdue University. Prosolia employs mass spectrometers to separate and isolate proteins for the production of consumable microarrays. Prosolia’s technology platforms include a proprietary ionization method that maintains macromolecular and protein conformation and function. The company holds several patents in these areas. For more information on Prosolia, visit www.prosolia.com or contact Dr. John Campbell, president and CEO at 317-278-6111 or email busallianc@aol.com

About Inproteo:
Inproteo LLC is the operating company of the Indiana Proteomics Consortium, a partnership formed between Eli Lilly and Company, Indiana University, and Purdue University to commercialize cutting-edge research in proteomic tools and analytical methods. In addition to Lilly’s significant research and development capabilities, the analytical chemistry departments of Indiana University and Purdue are ranked among the nation’s top four. Drawing on these resources, Inproteo has filed 55 patents and formed three companies since its inception. For more information on Inproteo, visit www.inproteo.com or contact Dr. John Hurrell, President at 317-278-8185 or email jghurrel@iupui.edu